Dental pulp stem cell (DPSC) isolation, characterization, and differentiation.

  title={Dental pulp stem cell (DPSC) isolation, characterization, and differentiation.},
  author={Federico Ferro and Renza Spelat and Chelsea S Baheney},
  journal={Methods in molecular biology},
Dental pulp stem cells (DPSC) have been proposed as an alternative to pluripotent stem cells to study multilineage differentiation in vitro and for therapeutic application. Standard culture media for isolation and expansion of stem cells includes animal sera or animal-derived matrix components (e.g., Matrigel(®)). However, animal-derived reagents raise significant concerns with respect to the translational ability of these cells due to the possibility of infection and/or severe immune reaction… CONTINUE READING
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