Dental mesenchymal stem cells encapsulated in an alginate hydrogel co-delivery microencapsulation system for cartilage regeneration.
@article{Moshaverinia2013DentalMS, title={Dental mesenchymal stem cells encapsulated in an alginate hydrogel co-delivery microencapsulation system for cartilage regeneration.}, author={A. Moshaverinia and X. Xu and C. Chen and K. Akiyama and M. Snead and S. Shi}, journal={Acta biomaterialia}, year={2013}, volume={9 12}, pages={ 9343-50 } }
Dental-derived mesenchymal stem cells (MSCs) are promising candidates for cartilage regeneration, with a high capacity for chondrogenic differentiation. This property helps make dental MSCs an advantageous therapeutic option compared to current treatment modalities. The MSC delivery vehicle is the principal determinant for the success of MSC-mediated cartilage regeneration therapies. The objectives of this study were to: (1) develop a novel co-delivery system based on TGF-β1 loaded RGD-coupled… CONTINUE READING
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References
SHOWING 1-10 OF 33 REFERENCES
Alginate hydrogel as a promising scaffold for dental-derived stem cells: an in vitro study
- Materials Science, Medicine
- Journal of Materials Science: Materials in Medicine
- 2012
- 87
Enhanced MSC chondrogenesis following delivery of TGF-β3 from alginate microspheres within hyaluronic acid hydrogels in vitro and in vivo.
- Materials Science, Medicine
- Biomaterials
- 2011
- 263
- PDF
Chondrogenesis of human mesenchymal stem cells encapsulated in alginate beads.
- Materials Science, Medicine
- Journal of biomedical materials research. Part A
- 2003
- 212
- PDF
The effect of immobilized RGD peptide in macroporous alginate scaffolds on TGFbeta1-induced chondrogenesis of human mesenchymal stem cells.
- Materials Science, Medicine
- Biomaterials
- 2010
- 142
Chondrogenic potential of human synovial mesenchymal stem cells in alginate.
- Chemistry, Medicine
- Osteoarthritis and cartilage
- 2007
- 127
Cell Encapsulating Biomaterial Regulates Mesenchymal Stromal/Stem Cell Differentiation and Macrophage Immunophenotype
- Chemistry, Medicine
- Stem cells translational medicine
- 2012
- 34
Cell-interactive Alginate Hydrogels for Bone Tissue Engineering
- Chemistry, Medicine
- Journal of dental research
- 2001
- 467
A rapid-curing alginate gel system: utility in periosteum-derived cartilage tissue engineering.
- Materials Science, Medicine
- Biomaterials
- 2004
- 262
The enhancement of chondrogenic differentiation of human mesenchymal stem cells by enzymatically regulated RGD functionalities.
- Materials Science, Medicine
- Biomaterials
- 2008
- 268
Chondrogenic differentiation of human mesenchymal stem cells in three-dimensional alginate gels.
- Chemistry, Medicine
- Tissue engineering. Part A
- 2008
- 189
- PDF