Dental considerations in the patient with Wilson's disease.

@article{Lohe2011DentalCI,
  title={Dental considerations in the patient with Wilson's disease.},
  author={Vidya Krushnarao Lohe and Ravindra P Kadu and Shirish S. Degwekar and Rahul Rajaram Bhowate and Anil K Wanjari and Suwarna B Dangore},
  journal={Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics},
  year={2011},
  volume={111 1},
  pages={20-3}
}
Wilson's disease was described by Wilson in 1912. It is an autosomal recessive disorder caused by mutations in the ATP7B gene, a membrane-bound copper transporting ATPase. The deficiency of ATP7B protein impairs the biliary copper excretion, resulting in positive copper balance, hepatic copper accumulation, and copper toxicity from oxidant damage. The… CONTINUE READING