Dental and craniofacial characteristics in a patient with leprechaunism treated with insulin-like growth factor-I.

@article{Fukunaga2008DentalAC,
  title={Dental and craniofacial characteristics in a patient with leprechaunism treated with insulin-like growth factor-I.},
  author={Tomohiro Fukunaga and Takashi Murakami and Hiroyuki Tanaka and Shouichi Miyawaki and Takashi Yamashiro and Teruko Takano-Yamamoto},
  journal={The Angle orthodontist},
  year={2008},
  volume={78 4},
  pages={745-51}
}
Leprechaunism is an autosomal recessive disease characterized by elfin-like faces, loss of glucose homeostasis, and severe insulin resistance. This disease is caused by inherited defects of the insulin receptor and is lethal early in life. Perhaps for this reason, the teeth and craniofacial features of patients with leprechaunism have never been reported. In the present case, the patient had been diagnosed with leprechaunism with mutation in the insulin receptor gene and had treatment with… CONTINUE READING