Density of newly synthesized plasma membrane proteins in intracellular membranes. I. Stereological studies

  title={Density of newly synthesized plasma membrane proteins in intracellular membranes. I. Stereological studies},
  author={Gareth Griffiths and Graham Warren and Patrick Quinn and Odile Mathieu-Costello and Hans H Hoppeler},
  journal={The Journal of Cell Biology},
  pages={2133 - 2141}
As the spike proteins of Semliki Forest virus (SFV) pass from their site of synthesis in the endoplasmic reticulum (ER) to the cell surface, they must be concentrated and freed from endogenous proteins. To determine the magnitude of this sorting process we have measured the density of spike proteins in membranes of the intracellular transport pathway. In this first paper, using stereological procedures, we have estimated the surface areas of the ER, Golgi complex, and plasma membrane of… CONTINUE READING

From This Paper

Figures, tables, results, connections, and topics extracted from this paper.
56 Extracted Citations
27 Extracted References
Similar Papers

Citing Papers

Publications influenced by this paper.
Showing 1-10 of 56 extracted citations

Referenced Papers

Publications referenced by this paper.
Showing 1-10 of 27 references

Dissection of the Golgi complex . 1 . Monensin inhibits thetransport of viral membrane proteins from medial to trans Golgi cistemae in Baby hamster kidney cells infected with Semliki Forest virus

  • H. J. G. Gunderson
  • J . Cell Biol .
  • 1983

Dissection of the Golgi complex . lh Density separation of specific Golgi functions in virally infected cells treated with monensin

  • P. Quinn, G. Griffiths
  • J . Cell Biol .
  • 1983

Comparison of two subsampling methods for electron microscopic morphometry

  • G. E. Palade
  • J . Microsc .
  • 1981

Morphometric analysis of the membranes and organelles of small intestine enterocytes . 11 . Lipid fed hamsters

  • W. G. Cochran
  • J . Ultrastruct . Res .
  • 1981

Resolutioneffects on the stereological estimation of surface and volume and its interpretation in terms of fractal dimensions

  • Losa, E. R. Weibel
  • J. Microsc
  • 1981

Sampling designs forstereology

  • M. G. Farquhar
  • J . Microsc .
  • 1981

Similar Papers

Loading similar papers…