Density-dependent enhanced replication of a densovirus in Wolbachia-infected Aedes cells is associated with production of piRNAs and higher virus-derived siRNAs.

@article{Parry2019DensitydependentER,
  title={Density-dependent enhanced replication of a densovirus in Wolbachia-infected Aedes cells is associated with production of piRNAs and higher virus-derived siRNAs.},
  author={Rhys Harold Parry and Cameron R. Bishop and Lachlan de Hayr and Sassan Asgari},
  journal={Virology},
  year={2019},
  volume={528},
  pages={
          89-100
        }
}
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28 Citations
Highly Influential Citations
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28 Citations

Effect of Wolbachia wAlbB on a positive-sense RNA negev-like virus: a novel virus persistently infecting Aedes albopictus mosquitoes and cells.

This study explored the effect of Wolbachia on the virome of the Ae.

Transcriptional Response ofWolbachia to Dengue Virus Infection in Cells of the Mosquito Aedes aegypti

Wolbachia elicits a transcriptional response to virus infection and is identified mostly at the early stages of virus infection, highlighting Wolbachia’s ability to alter its gene expression in response to DENV infection of the host cell.

Persistent Spodoptera frugiperda rhabdovirus infection in Sf9 cells is not restricted by Wolbachia wMelPop-CLA and wAlbB strains and is targeted by the RNAi machinery.

Transcriptional Response of Wolbachia to Dengue Virus Infection in Cells of the Mosquito Aedes aegypti

Wolbachia elicits a transcriptional response to virus infection and is identified mostly at the early stages of virus infection, highlighting Wolbachia’s ability to alter its gene expression in response to DENV infection of the host cell.

Wolbachia RNase HI contributes to virus blocking in the mosquito Aedes aegypti

Endogenous viral element-derived piRNAs are not required for production of ping-pong-dependent piRNAs from Diaphorina citri densovirus

It is found that a Diaphorina citri densovirus-derived EVE gives rise to DcDV-specific primary piRNAs and is unevenly distributed among D. citri populations, representing the first report of ping-pong-dependent vpiRNAs outside of mosquitoes.

Wolbachia modulates prevalence and viral load of Culex pipiens densoviruses in natural populations

Analyzing the interactions between a widely prevalent ISV, the Culex pipiens densovirus (CpDV, Densovirinae), and Wolbachia in northern Tunisian C. pipiens populations provided good evidence for an ecological influence of WolbachIA on anISV, CpDVs, in natural populations and highlighted the importance of integrating Wolbachias in the understanding of ISV ecology in nature.

Analysis of Aedes aegypti microRNAs in response to Wolbachia wAlbB infection and their potential role in mosquito longevity

By selectively inhibiting some differentially expressed miRNAs, some of which showed greater upregulation in wAlbB-infected mosquitoes than in tetracycline cleared ones, it is identifiedMiR-2946-3p and miR-317-3P as effecting mosquito longevity in Wolbachia-infecting mosquitoes.

Endogenous Viral Element-Derived Piwi-Interacting RNAs (piRNAs) Are Not Required for Production of Ping-Pong-Dependent piRNAs from Diaphorina citri Densovirus

It is shown that piRNAs target a DNA virus, but not RNA viruses, in an agricultural insect pest, and it is demonstrated that viruses can be targeted by PiRNAs in a nonmosquito species independently of endogenous pi RNAs.

Identification and RNAi Profile of a Novel Iflavirus Infecting Senegalese Aedes vexans arabiensis Mosquitoes

Insight is provided into the diversity of commensal Aedes viruses and the host RNAi response towards iflaviruses and the RT-PCR screens of archival and current Ae.

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