Densely adherent growth mode, rather than extracellular polymer substance matrix build-up ability, contributes to high resistance of Staphylococcus epidermidis biofilms to antibiotics.

@article{Qu2010DenselyAG,
  title={Densely adherent growth mode, rather than extracellular polymer substance matrix build-up ability, contributes to high resistance of Staphylococcus epidermidis biofilms to antibiotics.},
  author={Yue Qu and Andrew J. Daley and Taghrid Istivan and Duncan A. Rouch and Margaret A. Deighton},
  journal={The Journal of antimicrobial chemotherapy},
  year={2010},
  volume={65 7},
  pages={1405-11}
}
OBJECTIVES (i) To evaluate the role of the adherent growth mode and extracellular polymer substance build-up in biofilm resistance to antibiotics. (ii) To re-assess various mechanisms leading to biofilm resistance to antibiotics. METHODS We compared the biofilm MICs, biofilm MBCs using the viable count method, biofilm MBCs based on broth recovery methods and minimum biofilm eradication concentrations (MBECs) of antistaphylococcal antibiotics for multilayer biofilms formed by 'biofilm-positive… CONTINUE READING

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