Dense mapping of IL18 shows no association in SLE

  title={Dense mapping of IL18 shows no association in SLE},
  author={Sandra G Guerra and David Lester Morris and Vesela Gateva and Robert R. Graham and Timothy J Vyse and Deborah S Cunninghame Graham},
  booktitle={Human molecular genetics},
Systemic lupus erythematosus (SLE) is an autoimmune disease which behaves as a complex genetic trait. At least 20 SLE risk susceptibility loci have been mapped using both candidate gene and genome-wide association strategies. The gene encoding the pro-inflammatory cytokine, IL18, has been reported as a candidate gene showing an association with SLE. This… CONTINUE READING