Dense-map genome scan for dyslexia supports loci at 4q13, 16p12, 17q22; suggests novel locus at 7q36.

@article{Field2013DensemapGS,
  title={Dense-map genome scan for dyslexia supports loci at 4q13, 16p12, 17q22; suggests novel locus at 7q36.},
  author={Lanora Leigh Field and Karey Shumansky and Jason W Ryan and Darwin Truong and E. Swiergala and Bonnie J. Kaplan},
  journal={Genes, brain, and behavior},
  year={2013},
  volume={12 1},
  pages={56-69}
}
Analysis of genetic linkage to dyslexia was performed using 133,165 array-based SNPs genotyped in 718 persons from 101 dyslexia-affected families. Results showed five linkage peaks with lod scores >2.3 (4q13.1, 7q36.1-q36.2, 7q36.3, 16p12.1, and 17q22). Of these five regions, three have been previously implicated in dyslexia (4q13.1, 16p12.1, and 17q22), three have been implicated in attention-deficit hyperactivity disorder (ADHD, which highly co-occurs with dyslexia; 4q13.1, 7q36.3, 16p12.1… CONTINUE READING
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