Dense lymphocytic infiltrates associated with non-melanoma skin cancer in patients with chronic lymphocytic leukemia.

@article{Wilson2010DenseLI,
  title={Dense lymphocytic infiltrates associated with non-melanoma skin cancer in patients with chronic lymphocytic leukemia.},
  author={Morgan L. Wilson and Dirk Michael Elston and William B. Tyler and Victor J Marks and Tammie C. Ferringer},
  journal={Dermatology online journal},
  year={2010},
  volume={16 3},
  pages={4}
}
Chronic lymphocytic leukemia (CLL) is a common hematologic malignancy associated with an increased risk of non-melanoma skin cancer. Basal cell carcinomas and squamous cell carcinomas in these patients may have an associated dense peritumoral leukemic infiltrate. This infiltrate can lead to the diagnosis of CLL and may also obscure tumor margins and pose a challenge in the assessment of perineural tumor spread. Immunohistochemical stains are useful in distinguishing leukemic B-cell infiltrates… CONTINUE READING