Dengue virus type 2 envelope protein displayed as recombinant phage attachment protein reveals potential cell binding sites.

Abstract

A method to map the specific site on dengue virus envelope protein (E) that interacts with cells and a neutralizing antibody is developed using serially truncated dengue virus type 2 (DENV-2) E displayed on M13 phages as recombinant E-g3p fusion proteins. Recombinant phages displaying the truncated E consisting of amino acids 297-423 (EB2) and amino acids… (More)
DOI: 10.1093/protein/gzn041

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