Dengue viremia in blood donors identified by RNA and detection of dengue transfusion transmission during the 2007 dengue outbreak in Puerto Rico.

@article{Stramer2012DengueVI,
  title={Dengue viremia in blood donors identified by RNA and detection of dengue transfusion transmission during the 2007 dengue outbreak in Puerto Rico.},
  author={Susan L. Stramer and Jeffrey M. Linnen and James M. Carrick and Gregory A. Foster and David Krysztof and Shimian Zou and Roger Y. Dodd and Lourdes M Tirado-Marrero and Elizabeth A. Hunsperger and Gilberto A. Santiago and Jorge Luis Mu{\~n}oz-Jord{\'a}n and Kay M Tomashek},
  journal={Transfusion},
  year={2012},
  volume={52 8},
  pages={
          1657-66
        }
}
BACKGROUND In 2007, a total of 10,508 suspected dengue cases were reported in Puerto Rico. Blood donations were tested for dengue virus (DENV) RNA and recipients of RNA-positive donations traced to assess transfusion transmission. STUDY DESIGN AND METHODS Blood donation samples from 2007 were maintained in a repository and tested individually for DENV RNA by transcription-mediated amplification (TMA); a subset was further tested by an enhanced TMA (eTMA) assay. TMA-reactive samples were… CONTINUE READING
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