Dengue and dengue hemorrhagic fever.

@article{Hayes1992DengueAD,
  title={Dengue and dengue hemorrhagic fever.},
  author={Edward B. Hayes and Duane J. Gubler},
  journal={The Pediatric infectious disease journal},
  year={1992},
  volume={11 4},
  pages={311-7}
}
Hundreds of thousands of dengue cases are reported worldwide each year. Given the difficulty in obtaining full reporting, the actual number of human infections is probably much higher than the number reported. Dengue is usually a nonspecific febrile illness that resolves with supportive therapy but the clinical spectrum ranges from asymptomatic infection through severe hemorrhage and sudden fatal shock. The pathophysiology of the severe forms of dengue may be related to sequential infection… CONTINUE READING
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