Dengue Virus Entry as Target for Antiviral Therapy

@inproceedings{Alen2012DengueVE,
  title={Dengue Virus Entry as Target for Antiviral Therapy},
  author={Marijke M. F. Alen and Dominique Schols},
  booktitle={Journal of tropical medicine},
  year={2012}
}
Dengue virus (DENV) infections are expanding worldwide and, because of the lack of a vaccine, the search for antiviral products is imperative. Four serotypes of DENV are described and they all cause a similar disease outcome. It would be interesting to develop an antiviral product that can interact with all four serotypes, prevent host cell infection and subsequent immune activation. DENV entry is thus an interesting target for antiviral therapy. DENV enters the host cell through receptor… CONTINUE READING

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