Dendritic spines: the locus of structural and functional plasticity.

  title={Dendritic spines: the locus of structural and functional plasticity.},
  author={Carlo Sala and Menahem Segal},
  journal={Physiological reviews},
  volume={94 1},
The introduction of high-resolution time lapse imaging and molecular biological tools has changed dramatically the rate of progress towards the understanding of the complex structure-function relations in synapses of central spiny neurons. Standing issues, including the sequence of molecular and structural processes leading to formation, morphological change, and longevity of dendritic spines, as well as the functions of dendritic spines in neurological/psychiatric diseases are being addressed… CONTINUE READING
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