Dendritic cells induce CD4+ and CD8+ T-cell responses to Mycobacterium bovis and M. avium antigens in Bacille Calmette Guérin vaccinated and nonvaccinated cattle.

@article{Hope2000DendriticCI,
  title={Dendritic cells induce CD4+ and CD8+ T-cell responses to Mycobacterium bovis and M. avium antigens in Bacille Calmette Gu{\'e}rin vaccinated and nonvaccinated cattle.},
  author={Jayne C Hope and Lai Shan Kwong and P. I. Sopp and Robert Alan Collins and Chris John Howard},
  journal={Scandinavian journal of immunology},
  year={2000},
  volume={52 3},
  pages={285-91}
}
Few data are available regarding the induction of memory T-lymphocyte responses in cattle following Bacille Calmette Guérin (BCG) vaccination. Studies of the immune response induced by BCG vaccination provide an insight into the basis of antimycobacterial immunity that could be exploited for the development of more effective vaccination strategies. We used autologous dendritic cells (DC) infected with Mycobacterium bovis Bacille Calmette Guérin (BCG) or pulsed with purified protein derivative… CONTINUE READING

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