Dendritic cells in cancer vaccines.

  title={Dendritic cells in cancer vaccines.},
  author={Peter Brossart and Stefan Wirths and W. E. Brugger and Lothar Kanz},
  journal={Experimental hematology},
  volume={29 11},
Dendritic cells (DC) are recognized as the most potent antigen-presenting cells with the ability to stimulate naive resting T cells and to initiate primary immune responses. Encouraging results in vaccination studies in animal models and the development of protocols to generate sufficient numbers of human DC for clinical application have led to attempts to verify the feasibility and efficacy of this approach in patients in the context of Phase I/II vaccination trials. This review aims to… CONTINUE READING

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