Dendritic cells in atherosclerosis: functions in immune regulation and beyond.

@article{Manthey2011DendriticCI,
  title={Dendritic cells in atherosclerosis: functions in immune regulation and beyond.},
  author={Helga D Manthey and Alma Zernecke},
  journal={Thrombosis and haemostasis},
  year={2011},
  volume={106 5},
  pages={772-8}
}
Chronic inflammation drives the development of atherosclerosis. Dendritic cells (DCs) are known as central mediators of adaptive immune responses and the development of immunological memory and tolerance. DCs are present in non-diseased arteries, and accumulate within atherosclerotic lesions where they can be localised in close vicinity to T cells. Recent work has revealed important functions of DCs in regulating immune mechanisms in atherogenesis, and vaccination strategies using DCs have been… CONTINUE READING

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