Dendritic cells co-localize with activated CD4+ T cells in giant cell arteritis.

@article{Wagner2003DendriticCC,
  title={Dendritic cells co-localize with activated CD4+ T cells in giant cell arteritis.},
  author={Annette Doris Wagner and Ulrike Wittkop and A. Prahst and Wolfgang Schmidt and E J Gromnica-ihle and Klaus Vorpahl and Alan P. Hudson and Henning K Zeidler},
  journal={Clinical and experimental rheumatology},
  year={2003},
  volume={21 2},
  pages={185-92}
}
OBJECTIVE Giant cell arteritis (GCA) is a vasculitis predominantly affecting medium- and large-sized arteries. Recent data show the co-localization of dendritic cells and Chlamydia pneumoniae in vascular biopsies from GCA patients. Here we define the topographical relation of dendritic cells and these activated T-cells to determine the antigen presenting cell in GCA, and to examine several auxiliary biochemical and genetic aspects relating to the role of bacteria such as C. pneumoniae in… CONTINUE READING
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