Dendritic cells as vectors for immunotherapy of tumor and its application for gastric cancer therapy.

@article{Wu2004DendriticCA,
  title={Dendritic cells as vectors for immunotherapy of tumor and its application for gastric cancer therapy.},
  author={Yugang Wu and Liang Wang and Yanyun Zhang},
  journal={Cellular & molecular immunology},
  year={2004},
  volume={1 5},
  pages={351-6}
}
Dendritic cells (DCs) are recognized as the most potent antigen-presenting cells (APCs) with the ability to stimulate naive resting T cells and initiate primary immune responses. DCs are poised to capture antigen (Ag), migrate to draining lymphoid organs, and, after a process of maturation, select Ag-specific lymphocytes to which they present the processed Ag, thereby inducing immune responses. Numerous studies indicated that immunotherapies utilizing DC-presenting tumor-associated antigens can… CONTINUE READING