Dendritic cells are required for the development of chronic eosinophilic airway inflammation in response to inhaled antigen in sensitized mice.

@article{Lambrecht1998DendriticCA,
  title={Dendritic cells are required for the development of chronic eosinophilic airway inflammation in response to inhaled antigen in sensitized mice.},
  author={Bart M. Lambrecht and Beno{\^i}t L. Salomon and David Klatzmann and Romain A. Pauwels},
  journal={Journal of immunology},
  year={1998},
  volume={160 8},
  pages={4090-7}
}
Asthma is characterized by chronic eosinophilic inflammation of the airways, and allergen-specific Th2 lymphocytes are thought to play a major role in the development and maintenance of this type of inflammation in allergic asthma. It is generally accepted that airway dendritic cells (DC) are essential for stimulating naive T cells in a primary immune response to inhaled Ag and for the development of allergic sensitization. We have examined the role of airway DC in stimulating memory T cells in… CONTINUE READING

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