Dendritic cells are early responders to retinal injury.

  title={Dendritic cells are early responders to retinal injury.},
  author={Ute Lehmann and Neal D. Heuss and Scott W. McPherson and Heidi Roehrich and Dale S Gregerson},
  journal={Neurobiology of disease},
  volume={40 1},
The presence and activity of dendritic cells (DC) in retina is controversial, as these cells are difficult to identify in retina due to limited markers and sparse numbers. Transgenic mice that express green fluorescent protein (GFP) on the CD11c promoter to label DC allowed the visualization and quantification of retinal DC. Two retina injury models, the optic nerve crush (ONC) and light injury, were used to study their injury response. Many GFP(+) DC were tightly associated with retinal… CONTINUE READING
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