Dendritic cells and the control of immunity

@article{Banchereau1998DendriticCA,
  title={Dendritic cells and the control of immunity},
  author={Jacques F. Banchereau and Ralph M. Steinman},
  journal={Nature},
  year={1998},
  volume={392},
  pages={245-252}
}
B and T lymphocytes are the mediators of immunity, but their function is under the control of dendritic cells. Dendritic cells in the periphery capture and process antigens, express lymphocyte co-stimulatory molecules, migrate to lymphoid organs and secrete cytokines to initiate immune responses. They not only activate lymphocytes, they also tolerize T cells to antigens that are innate to the body (self-antigens), thereby minimizing autoimmune reactions. Once a neglected cell type, dendritic… Expand
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