Dendritic cell vaccines for cancer immunotherapy.

@article{Timmerman1999DendriticCV,
  title={Dendritic cell vaccines for cancer immunotherapy.},
  author={John M. Timmerman and Ronald Levy},
  journal={Annual review of medicine},
  year={1999},
  volume={50},
  pages={507-29}
}
Human tumors express a number of protein antigens that can be recognized by T cells, thus providing potential targets for cancer immunotherapy. Dendritic cells (DCs) are rare leukocytes that are uniquely potent in their ability to present antigens to T cells, and this property has prompted their recent application to therapeutic cancer vaccines. Isolated DCs loaded with tumor antigen ex vivo and administered as a cellular vaccine have been found to induce protective and therapeutic anti-tumor… CONTINUE READING

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