Dendritic cell subtypes and in vitro generation of dendritic cells.

  title={Dendritic cell subtypes and in vitro generation of dendritic cells.},
  author={Benedikt Jacobs and Margret Wuttke and Claudia Papewalis and J{\"u}rgen Seissler and Matthias Schott},
  journal={Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme},
  volume={40 2},
Dendritic cells (DCs) are highly potent antigen-presenting cells crucial for the innate and adaptive immune response and for maintaining immune tolerance towards self-antigens. Although they share many common features, multiple DC subtypes with different immune functions have been identified. Originally, DCs were considered to be cells with purely myeloid origin. Recent studies have now demonstrated that DCs can also develop from lymphatic progenitors. Various cytokines and transcription… CONTINUE READING


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