Dendritic cell subsets in blood and lymphoid tissue of rhesus monkeys and their mobilization with Flt3 ligand.

@article{Coates2003DendriticCS,
  title={Dendritic cell subsets in blood and lymphoid tissue of rhesus monkeys and their mobilization with Flt3 ligand.},
  author={Patrick Toby Hewlett Coates and Simon M Barratt-Boyes and Linyou Zhang and Vera S Donnenberg and Peta J. O'Connell and Alison J. Logar and Felicity Duncan and Michael A. Murphey-Corb and Albert D. Donnenberg and Adrian E Morelli and Charles R. Maliszewski and Angus W Thomson},
  journal={Blood},
  year={2003},
  volume={102 7},
  pages={2513-21}
}
We provide phenotypic and functional evidence of premonocytoid dendritic cells (DCs) and preplasmacytoid DCs in blood and of corresponding DC subsets in secondary lymphoid tissue of rhesus monkeys. Subsets were identified and sorted by 4-color flow cytometry using antihuman monoclonal antibodies cross-reactive with rhesus monkey. To mobilize pre-DC subsets, fms-like tyrosine 3 kinase ligand (Flt3L; 100 microg/kg subcutaneously) was administered for 10 days. Presumptive pre-DC subsets were… CONTINUE READING