Dendritic cell regulation of immune responses: a new role for interleukin 2 at the intersection of innate and adaptive immunity.

@article{Granucci2003DendriticCR,
  title={Dendritic cell regulation of immune responses: a new role for interleukin 2 at the intersection of innate and adaptive immunity.},
  author={Francesca Granucci and Ivan Zanoni and Sonia Feau and Paola Ricciardi-Castagnoli},
  journal={The EMBO journal},
  year={2003},
  volume={22 11},
  pages={2546-51}
}
Dendritic cells are professional antigen-presenting cells able to initiate innate and adaptive immune responses against invading pathogens. In response to external stimuli dendritic cells undergo a complete genetic reprogramming that allows them to become, soon after activation, natural killer cell activators and subsequently T cell stimulators. The recent observation that dendritic cells produce interleukin 2 following microbial stimulation opens new possibilities for understanding the… CONTINUE READING

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