Dendritic cell development: multiple pathways to nature's adjuvants.

  title={Dendritic cell development: multiple pathways to nature's adjuvants.},
  author={Ken D Shortman and Christophe Caux},
  journal={Stem cells},
  volume={15 6},
Dendritic cells are a system of bone marrow-derived antigen-presenting cells specialized for interaction with T lymphocytes and essential for initiating primary T cell immune responses. Recent investigation indicates that dendritic cells are of diverse origin, with at least two types of myeloid precursors and a lymphoid precursor implicated in their generation. Mature dendritic cell subtypes, while sharing the capacity to activate T cells, show additional functional specialization. Some… CONTINUE READING


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