Dendritic cell biology.

  title={Dendritic cell biology.},
  author={Francesca Granucci and Maria Gabriella Foti and Paola Ricciardi-Castagnoli},
  journal={Advances in immunology},
Dendritic cells (DCs) are a special type of leukocytes able to alert the immune system to the presence of infections. They play a central role in the initiation of both innate and adaptive immune responses. This particular DC feature is regulated by the activation of specific receptors at the cell surface called Toll-like receptors (TLRs) that bind a number of microbial products collectively referred to as microbial-associated molecular patterns (MAMP). TLRs initiate a cascade of events, which… CONTINUE READING


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