Dendritic cell-based vaccines: clinical applications in breast cancer.

  title={Dendritic cell-based vaccines: clinical applications in breast cancer.},
  author={Lucia Gelao and Carmen Criscitiello and Angela Esposito and Michele De Laurentiis and Luca A. M. Fumagalli and Marzia Adelia Locatelli and Ida Minchella and M. Soledad P{\'e}rez Santangelo and Sabino De Placido and Aron Goldhirsch and Giuseppe Curigliano},
  volume={6 3},
Recent evidence suggests that the immune system is involved in the carcinogenesis process and the antitumor immune responses impact the clinical outcome, thus emphasizing the concept of cancer immune surveillance. In this context, dendritic cells (DCs) seem to play a crucial role, as they are the most potent antigen-presenting cells (APCs) and are able to stimulate naive T lymphocytes and to generate memory T lymphocytes. Immunotherapy with DC-based vaccines is a very attractive approach to… CONTINUE READING
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