Dendritic calcium spikes are clearly detectable at the cortical surface

@inproceedings{Suzuki2017DendriticCS,
  title={Dendritic calcium spikes are clearly detectable at the cortical surface},
  author={Mototaka Suzuki and Matthew Evan Larkum},
  booktitle={Nature Communications},
  year={2017}
}
Cortical surface recording techniques such as EEG and ECoG are widely used for measuring brain activity. The prevailing assumption is that surface potentials primarily reflect synaptic activity, although non-synaptic events may also contribute. Here we show that dendritic calcium spikes occurring in pyramidal neurons (that we showed previously are cognitively relevant) are clearly detectable in cortical surface potentials. To show this we developed an optogenetic, non-synaptic approach to evoke… CONTINUE READING

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