Dendritic actin filament nucleation causes traveling waves and patches.

@article{Carlsson2010DendriticAF,
  title={Dendritic actin filament nucleation causes traveling waves and patches.},
  author={Anders E. Carlsson},
  journal={Physical review letters},
  year={2010},
  volume={104 22},
  pages={
          228102
        }
}
The polymerization of actin via branching at a cell membrane containing nucleation-promoting factors is simulated using a stochastic-growth methodology. The polymerized-actin distribution displays three types of behavior: (a) traveling waves, (b) moving patches, and (c) random fluctuations. Increasing actin concentration causes a transition from patches to waves. The waves and patches move by a treadmilling mechanism not involving myosin II. The effects of downregulation of key proteins on… CONTINUE READING

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