Dendritic Integration in Olfactory Sensory Neurons: A Steady-State Analysis of How the Neuron Structure and Neuron Environment Influence the Coding of Odor Intensity

@article{Vermeulen2004DendriticII,
  title={Dendritic Integration in Olfactory Sensory Neurons: A Steady-State Analysis of How the Neuron Structure and Neuron Environment Influence the Coding of Odor Intensity},
  author={Arthur Vermeulen and Jean-Pierre Rospars},
  journal={Journal of Computational Neuroscience},
  year={2004},
  volume={5},
  pages={243-266}
}
Response properties of the receptor potential at steady state were analyzed in a biophysical model of an olfactory sensory neuron embedded in a multicell environment. The neuron structure was described as a set of several identical dendrites (or cilia) bearing the transduction mechanisms, joined to a nonsensory part—dendritic knob, soma, and axon. The different ionic compositions of the media surrounding the neuron sensory and nonsensory parts and the extraneuronal voltage sources, which both… 
Dynamical Modeling of the Moth Pheromone-Sensitive Olfactory Receptor Neuron within Its Sensillar Environment
TLDR
The model presented takes into account both the molecular processes of ORNs and the cellular organization and compartmentalization of the organ represented by an electrical circuit, and provides a quantitative description of the spatial and temporal evolution of the pheromone-dependent conductances, currents and potentials along the outer dendrite.
Why are insect olfactory receptor neurons grouped into sensilla? The teachings of a model investigating the effects of the electrical interaction between neurons on the transepithelial potential and the neuronal transmembrane potential
TLDR
It is found that gathering neurons in the same sensillum is disadvantageous if they are identical, but can be advantageous if their thresholds differ, and application of these results to actual recordings from pheromone and food-odour olfactory sensilla is discussed.
Relation between stimulus and response in frog olfactory receptor neurons in vivo
TLDR
Receptor activation and ciliary membrane conductance were reconstructed in the framework of a model based on firing data, known mucus biochemical and neuron morpho‐electrical characteristics and describes their statistical distributions in the neuron population.
Neuronal and Glial Morphology in Olfactory Systems: Significance for Information-Processing and Underlying Developmental Mechanisms
TLDR
The findings reviewed here suggest that specialized cellular architecture plays key functional roles in the detection, analysis, and discrimination of odors at early steps in olfactory processing.
Modeling the response of a population of olfactory receptor neurons to an odorant
We modeled the firing rate of populations of olfactory receptor neurons (ORNs) responding to an odorant at different concentrations. Two cases were considered: a population of ORNs that all express
Biophysics of olfaction
TLDR
A large number of representative biophysical efforts in olfaction, their main contributions, the trends for the next generations of biophysical models and the improvements that may be explored by future biophysicists of Olfaction have been reviewed.
Computation in the olfactory system.
TLDR
This review will attempt to provide a comprehensive, functional overview of computational ideas in olfaction and outline a computational framework for olfactory processing based on the insights provided by these diverse models and their supporting data.
Detection of amyotrophic lateral sclerosis using signal processing and machine learning
TLDR
This paper proposes a method for classification of ALS based on evaluation of multiple features extracted from three domains of EMG signal: time domain representation, frequency domain representation and Muscle Unit Action Potential waveform acquired via EMG decomposition of the signal.
Role of web enabled Digital Scent Technology
---What if you could send the smell of amazing spice and curry with the picture? What if you open the picture of flowers on your computer and the amazing smell fills the air around you. Approximately
...
...

References

SHOWING 1-10 OF 46 REFERENCES
Coding of odor intensity in a steady-state deterministic model of an olfactory receptor neuron
TLDR
An optimal encoder neuron is presented that suggests that increasing the length of the sensory dendrite beyond about 0.3 space constant does not increase the magnitude of the receptor potential, and the overall gain in sensitivity results entirely from the conductance-to-voltage conversion.
Coding of stimulus intensity in an olfactory receptor neuron: Role of neuron spatial extent and passive dendritic backpropagation of action potentials
The olfactory receptor neuron provides a good opportunity to analyze a biophysical model of a single neuron because its dendritic structure is simple and even close to a cylinder in the case of the
Functional properties of vertebrate olfactory receptor neurons.
TLDR
Several lines of evidence support the hypothesis that the initial molecular events and subsequent stages of transduction are mediated by odorant receptor sites and associated ion channels located in the membrane of the cilia and apical dendritic knob of the olfactory receptor neuron.
Coding of odour intensity in a sensory neuron.
Intensity Coding in an Olfactory Sensory Neuron
Coding properties at steady-state of the receptor potential were analyzed in a biophysical model of an olfactory neuron with and without taking into account the auxiliary cells that surround it. It
Chemo-electrical transduction in insect olfactory receptors.
TLDR
Electrophysiological investigations of cellular response charac­ teristics as well as biophysical and biochemical work, much of which is based on radiolabeled pheromone compounds are covered, mainly of moths with olfactory organs that are relatively large and accessible for experimental work.
Electrotonic structure of olfactory sensory neurons analyzed by intracellular and whole cell patch techniques.
TLDR
The prediction that even small values of electrode shunt have relatively large effects on the recorded electrotonic properties of small neurons is confirmed, because of their high RN (2-5 G omega).
Coding of odor intensity.
The electrical circuitry of an olfactory sensillum in Antheraea polyphemus
TLDR
Dendrite amputation experiments showed that the impedance of the dendrite does not limit the spike amplitude and that the dendsrite contributes slightly to the duration of the positive phases of spikes, indicating that thedendrite is also involved in the generation of the leading phase of the spike.
...
...