Dendritic Cells: Sentinels of Immunity and Tolerance

@article{Kubach2005DendriticCS,
  title={Dendritic Cells: Sentinels of Immunity and Tolerance},
  author={J. Kubach and C. Becker and E. Schmitt and K. Steinbrink and E. Huter and A. Tuettenberg and H. Jonuleit},
  journal={International Journal of Hematology},
  year={2005},
  volume={81},
  pages={197-203}
}
The induction of effective antigen-specific T-cell immunity to pathogens without the initiation of autoimmunity has evolved as a sophisticated and highly balanced immunoregulatory mechanism. This mechanism assures the generation of antigen-specific effector cells as well as the induction and maintenance of antigen-specific tolerance to self-structures of the body. As professional antigen-presenting cells of the immune system, dendritic cells (DC) are ideally positioned throughout the entire… Expand
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