Dendritic Cells: A Double-Edged Sword in Immune Responses during Chagas Disease

@article{GilJaramillo2016DendriticCA,
  title={Dendritic Cells: A Double-Edged Sword in Immune Responses during Chagas Disease},
  author={Natalia Gil-Jaramillo and F. N. Motta and C. Favali and I. D. Bastos and J. Santana},
  journal={Frontiers in Microbiology},
  year={2016},
  volume={7}
}
Dendritic cells (DCs) are the most important member of the antigen presenting cells group due to their ability to recognize antigen at the infection site and their high specialized antigen internalization capacity. These cells have central role in connecting the innate and adaptive immune responses against Trypanosoma cruzi, the causative agent of Chagas disease. These first line defense cells modulate host immune response depending on type, maturation level, cytokine milieu and DC receptor… Expand
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