Dendritic Cell Numbers in the Blood of HIV-1 Infected Patients Before and After Changes in Antiretroviral Therapy

@article{Finke2004DendriticCN,
  title={Dendritic Cell Numbers in the Blood of HIV-1 Infected Patients Before and After Changes in Antiretroviral Therapy},
  author={Jennifer S. Finke and Michael Shodell and Kokila C. Shah and Frederick P. Siegal and Ralph Marvin Steinman},
  journal={Journal of Clinical Immunology},
  year={2004},
  volume={24},
  pages={647-652}
}
Antigen presenting dendritic cells (DCs) can serve as sites for HIV replication and as vehicles for transmission of the virus to T cells. It is known that the numbers of DCs in blood is reduced during HIV-1 infection. Here we monitored the two major subsets of blood DCs in 12 individuals undergoing a change, primarily initiation, of highly active antiretroviral therapy. The numbers of plasmacytoid DCs were reliably higher on therapy, although in the 1–3 month interval we followed, these numbers… CONTINUE READING
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Reduced blood

  • J Pacanowski, S Kahi, +7 authors A Hosmalin
  • Journal of Clinical Immunology,
  • 2004

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