Dendritic Cell Activation by Glucan Isolated from Umbilicaria Esculenta

  title={Dendritic Cell Activation by Glucan Isolated from Umbilicaria Esculenta},
  author={Hyung Sook Kim and Jee Youn Kim and Hong Kyung Lee and Moo Sung Kim and Sang Rin Lee and Jong Soon Kang and Hwan-Mook Kim and Kyung-Ae Lee and Jin Tae Hong and Youngsoo Kim and Sang Bae Han},
  journal={Immune Network},
  pages={188 - 197}
Background Lichen-derived glucans have been known to stimulate the functions of immune cells. However, immunostimulatory activity of glucan obtained from edible lichen, Umbilicaria esculenta, has not been reported. Thus we evaluated the phenotype and functional maturation of dendritic cells (DCs) following treatment of extracted glucan (PUE). Methods The phenotypic and functional maturation of PUE-treated DCs was assessed by flow cytometric analysis and cytokine production, respectively. PUE… 

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