Dendrimers in drug delivery and targeting: Drug-dendrimer interactions and toxicity issues

  title={Dendrimers in drug delivery and targeting: Drug-dendrimer interactions and toxicity issues},
  author={Kanika Madaan and Sandeep Kumar and Neelam Poonia and Viney Lather and Deepti Pandita},
  booktitle={Journal of pharmacy & bioallied sciences},
Dendrimers are the emerging polymeric architectures that are known for their defined structures, versatility in drug delivery and high functionality whose properties resemble with biomolecules. These nanostructured macromolecules have shown their potential abilities in entrapping and/or conjugating the high molecular weight hydrophilic/hydrophobic entities by host-guest interactions and covalent bonding (prodrug approach) respectively. Moreover, high ratio of surface groups to molecular volume… CONTINUE READING
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