Demyelination patterns in a mathematical model of multiple sclerosis.

Abstract

In this paper we derive a reaction-diffusion-chemotaxis model for the dynamics of multiple sclerosis. We focus on the early inflammatory phase of the disease characterized by activated local microglia, with the recruitment of a systemically activated immune response, and by oligodendrocyte apoptosis. The model consists of three equations describing the… (More)
DOI: 10.1007/s00285-016-1087-0

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