Demyelination and axonal degeneration in Lewis rat experimental allergic neuritis depend on the myelin dosage.

@article{Hahn1988DemyelinationAA,
  title={Demyelination and axonal degeneration in Lewis rat experimental allergic neuritis depend on the myelin dosage.},
  author={Angelika F G Hahn and Thomas E. Feasby and Ann Steele and D S Lovgren and Jacqueline Berry},
  journal={Laboratory investigation; a journal of technical methods and pathology},
  year={1988},
  volume={59 1},
  pages={115-25}
}
We describe the clinical and pathologic features of experimental allergic neuritis in Lewis rats inoculated with varying doses of myelin, ranging from 0.5 to 20 mg. The clinical scores were assessed daily. On days 18 and 19 or 28 postimmunization, the rats were perfused with fixative and samples of cervical and lumbar roots and sciatic nerves were processed and embedded in Epon. Tissues were examined by light and electron microscopy and the degree of edema, inflammation, demyelination, and… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 14 extracted citations

Similar Papers

Loading similar papers…