Demyelinating plaques in relapsing-remitting and secondary-progressive multiple sclerosis: assessment with diffusion MR imaging.

@article{Scanderbeg2000DemyelinatingPI,
  title={Demyelinating plaques in relapsing-remitting and secondary-progressive multiple sclerosis: assessment with diffusion MR imaging.},
  author={A Castriota Scanderbeg and Francesco Tomaiuolo and Umberto Sabatini and Ugo Nocentini and Maria Grazia Grasso and Carlo Caltagirone},
  journal={AJNR. American journal of neuroradiology},
  year={2000},
  volume={21 5},
  pages={862-8}
}
BACKGROUND AND PURPOSE Conventional MR imaging does not provide specific information that can be reliably associated with the pathologic substrate and clinical status of patients with multiple sclerosis (MS). Our goals were 1) to determine whether the orientationally averaged water diffusion coefficient () can be used to distinguish between plaques of different severity in these patients and 2) to assess possible correlations between values and disease duration, Expanded Disability Status… CONTINUE READING
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