Demyelinating CMT--what's known, what's new and what's in store?

  title={Demyelinating CMT--what's known, what's new and what's in store?},
  author={Kathryn M. Brennan and Yunhong Bai and Michael E. Shy},
  journal={Neuroscience letters},
Inherited neuropathies known collectively as Charcot-Marie-Tooth disease are one of the most common inherited neurological conditions affecting ∼1 in 2500 people. A heterogenous disorder, CMT is divided into subtypes based on the pattern of inheritance and also by neurophysiological studies. Despite the clinical similarities among patients with demyelinating CMT, it is recognized that this group of disorders is both genetically and phenotypically heterogenous. Understanding the pathogenesis of… CONTINUE READING


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