Demonstration of xanthine oxidase in human heart.

  title={Demonstration of xanthine oxidase in human heart.},
  author={S Abadeh and P C Case and Roger C. Harrison},
  journal={Biochemical Society transactions},
  volume={20 4},
The enzyme, xanthine oxidase, has become a focus of research activity because of its proposed role as a source of destructive free radicals in ischaemia reperfusion injury [l]. The presence of xanthine oxidase in human heart is, however, controversial in that several groups [2-51 have failed to find significant enzyme activity, despite two reports to the contrary [6,7] and its accepted presence in rat and dog hearts. We now report the immunoprecipitation of xanthine oxidase from post-mortem… CONTINUE READING