Demonstration of proton-transfer reaction time-of-flight mass spectrometry for real-time analysis of trace volatile organic compounds.

@article{Blake2004DemonstrationOP,
  title={Demonstration of proton-transfer reaction time-of-flight mass spectrometry for real-time analysis of trace volatile organic compounds.},
  author={Robert S. Blake and Christopher E. Whyte and Ceri O Hughes and Andrew M Ellis and Paul S Monks},
  journal={Analytical chemistry},
  year={2004},
  volume={76 13},
  pages={3841-5}
}
A proton-transfer reaction mass spectrometer based on time-of-flight mass spectrometry is described. This instrument couples a radioactive ion source and drift tube with a reflectron time-of-flight mass spectrometer. Volatile organic compounds in the gas phase with concentrations at the parts per billion by volume level can be detected in a matter of seconds, and crucially, the multichannel data acquisition in TOF-MS means that this detection sensitivity is available in all mass channels… CONTINUE READING
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