Demonstration of previously undetected hepatitis B viral determinants in an Australian Aboriginal population by monoclonal anti-hbs antibody radioimmunoassays.

@article{Wands1982DemonstrationOP,
  title={Demonstration of previously undetected hepatitis B viral determinants in an Australian Aboriginal population by monoclonal anti-hbs antibody radioimmunoassays.},
  author={Jack R Wands and Robert A Marciniak and Kurt J Isselbacher and Mani Varghese and G Don and June W. Halliday and Lawrie William Powell},
  journal={Lancet},
  year={1982},
  volume={1 8279},
  pages={977-80}
}
High-affinity IgM and IgG monoclonal antibodies (anti-HBs) against hepatitis B surface antigen (HBsAg) determinants were used to study a confined Australian Aboriginal population, 51% of which showed evidence of exposure to hepatitis B virus (HBV). A conventional radioimmunoassay which uses polyvalent anti-HBs antisera indicated that 4.4% of the subjects… CONTINUE READING