Demonstration of cytomegalovirus (CMV) DNA and anti-CMV response in the synovial membrane and serum of patients with rheumatoid arthritis.

@article{Einsele1992DemonstrationOC,
  title={Demonstration of cytomegalovirus (CMV) DNA and anti-CMV response in the synovial membrane and serum of patients with rheumatoid arthritis.},
  author={Hermann Einsele and Michael Steidle and Claudia Anna M{\"u}ller and Peter Fritz and J. Zacher and Helmuth Schmidt and Johannes Georg Saal},
  journal={The Journal of rheumatology},
  year={1992},
  volume={19 5},
  pages={677-81}
}
One hundred forty-seven synovial membranes were investigated for the presence of human cytomegalovirus (CMV). In 11 of 83 synovial membranes of patients with rheumatoid arthritis (RA), but only in 2 of 64 synovial membranes from patients with other joint disorders, CMV-DNA could be detected by the polymerase chain reaction (PCR) technique (p less than 0.05). In contrast, the percentage of seropositive patients was not significantly different between the 2 groups of patients and no blood sample… CONTINUE READING
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