Demonstration of a capsule plasmid in Bacillus anthracis.

@article{Green1985DemonstrationOA,
  title={Demonstration of a capsule plasmid in Bacillus anthracis.},
  author={Byron David Green and L Battisti and Theresa M Koehler and C B Thorne and Bruce E. Ivins},
  journal={Infection and immunity},
  year={1985},
  volume={49 2},
  pages={291-7}
}
Virulent and certain avirulent strains of Bacillus anthracis harbor a plasmid, designated pXO2, which is involved in the synthesis of capsules. Two classes of rough, noncapsulated (Cap-) variants were isolated from the capsule-producing (Cap+) Pasteur vaccine strains ATCC 6602 and ATCC 4229. One class was cured of pXO2, and the other class still carried it. Reversion to Cap+ was demonstrable only in rough variants which had retained pXO2. Proof that pXO2 is involved in capsule synthesis came… CONTINUE READING

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