Demographic history and linkage disequilibrium in human populations

@article{Laan1997DemographicHA,
  title={Demographic history and linkage disequilibrium in human populations},
  author={Mark ter Laan and Svante P{\"a}{\"a}bo},
  journal={Nature Genetics},
  year={1997},
  volume={17},
  pages={435-438}
}
In the human genome, linkage disequilibrium (LD)—the non-random association of alleles at chromosomal loci1—has been studied mainly in regions surrounding disease genes on affected chromosomes2–6. Consequently, little information is available on the distribution of LD across anonymous genomic regions in the general population. However, demographic history is expected to influence the extent of overall LD across the genome, so a population that has been of constant size will display higher… CONTINUE READING
BETA
Tweets
This paper has been referenced on Twitter 1 time. VIEW TWEETS

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
SHOWING 1-10 OF 93 CITATIONS, ESTIMATED 48% COVERAGE

205 Citations

01020'98'03'09'15
Citations per Year
Semantic Scholar estimates that this publication has 205 citations based on the available data.

See our FAQ for additional information.

Similar Papers

Loading similar papers…