Demographic and clinical parameters influencing the short-term outcome of anti-tumor necrosis factor (infliximab) treatment in Crohn's disease

@article{Vermeire2002DemographicAC,
  title={Demographic and clinical parameters influencing the short-term outcome of anti-tumor necrosis factor (infliximab) treatment in Crohn's disease},
  author={S{\'e}verine Vermeire and Edouard Louis and An Carbonez and Gert van Assche and M. Nasimul Noman and Jacques Belaiche and Martine de Vos and Andr{\'e} van Gossum and Paul Pescatore and R{\'e}n{\'e} Fiasse and Paul A. Pelckmans and Hendrik Reynaert and Geert R. A. M. D’Haens and P. R. Rutgeerts},
  journal={American Journal of Gastroenterology},
  year={2002},
  volume={97},
  pages={2357-2363}
}
OBJECTIVE:Infliximab is an effective treatment for refractory or fistulizing Crohn's disease (CD). However, about 30% of patients do not respond to infliximab for unknown reasons. Identifying predictive factors of response is important for optimizing clinical management and for better understanding infliximab's mechanisms of action. The aim of this study was to assess whether demographic or clinical parameters influence short-term response to infliximab.METHODS:The first 240 CD patients of the… CONTINUE READING
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