Demineralized bone matrix as a vehicle for delivering endogenous and exogenous therapeutics in bone repair.


As a unique human bone extract approved for implant use, demineralized bone matrix (DBM) retains substantial amounts of endogenous osteoconductive and osteoinductive proteins. Commercial preparations of DBM represent a clinically accessible, familiar, widely used and degradable bone-filling device, available in composite solid, strip/piece, and semi-solid… (More)
DOI: 10.1016/j.addr.2012.04.002


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